The Simpsons has become a meme of modern culture, and for that reason I could have simply said "Simpsons-esque drawing of a Mona Lisa" and immediately been understood by most non-under-rock-living human beings in (at least) the US. Thus, if we treat the show as such, the Jamesonian interpretation can be more fruitfully (or at least, efficiently) discussed. The Simpsons is a program that must be taken as a cooperative of a capitalist system because of its place within it. As a 20+ year (and running) old program, it has been accumulating cash for its mother company, FOX, for years. FOX, a nationally syndicated television network need not be brow-beatenly extrapolated as a "player" (and a talented one, at that) of the capitalist game, so this assumption will be made. Naturally, it cannot simply be surmised that "The Simpsons" is a deductively capitalist program, however, as a cash cow for FOX, it is an inherently capitalist-driven program. Thus, the very root of the program as an entity is capitalist. Now, while I can certainly appreciate the idea that The Simpsons can be seen as anti capitalist - whether in a particular quote, character, episode, or even the series' semiotic valuation as a whole - the context in which this particular image is presented is not in terms of a particular situation presented in the show. It is simply a pastiche of the Mona Lisa in the Simpsons style. It can also be extrapolated that not only is this a pastiche of the Mona Lisa, but also of the Simpsons themselves (itself?). Thus, a third degree of deduction is plausible. This degree will be likely be touched on briefly, but the main assumption I intend to present - in terms of Jameson - is that this is a by-product of the show itself and not a double-pastiche of the show and the painting.
Long-winded? In the words of Randy Bachman, "you ain't seen nothin' yet."
Jameson suggests that post-modernism is an extension and manifestation of "late capitalism." This "late" term inspires a linear periodization of capitalism. It suggests that capitalism is in its final stage. Thus, with Jameson's logic in mind, there is pre-Marxist capitalism, followed by Marist-inspired modernism, and finally concluded by the current post-modernism. Jameson follows this by suggesting an inherent misconception by both the "cultural critic and moralist" of "conceptualizing" post-modernism as a movement that rejects the (perceived) modernist aim of exposing the "'terrorism' on the social level" and instead concentrates its aims on "the cancer on the personal." With these in mind, it can be rightfully deduced that The Simpsons, as a post-modernist program, is aiming to reject the seminal modern work of the Mona Lisa, and instead create a situation in which this work is re-categorized as just another product. It creates a product where there was once art; as a simple cartoonish human being, it loses its value as a piece of art. Through a roundabout process of imposing its own representation of human beings, the woman is reduced to just that: a woman. The background is just a background, and all other meanings are lost via context. Jameson would likely be in tears over such an image, but I'll leave the evaluation of the emotions of his superego to the Freud scholars.